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Since the late 20th century there have been multiple reports of HIV/AIDS patients declared free of HIV infection following different treatment strategies. In 1989 an HIV-positive patient who had undergone allogeneic (nonself) hematopoietic stem cell transplantation (HSCT)—a procedure that entails the exchange of a patient’s blood-forming cells for those from a donor—for lymphoma was found to be HIV-negative following transplantation. The patient died shortly after from tumour relapse. The most-popularized case involved a 42-year-old man, Timothy Ray Brown, who had been cured of both leukemia and HIV, as described in 2009 in The New England Journal of Medicine. Brown, who ...(100 of 7006 words)