syphilis , Sexually transmitted disease caused by the spirochete Treponema pallidum. Without treatment, it may progress through three stages: primary, characterized by a chancre and low fever; secondary (weeks to months later; only half of those infected display symptoms), with a skin and mucous-membrane rash, lymph node swelling, and bone, joint, eye, and nervous system involvement; and tertiary. The tertiary stage follows a latency period that can last years, and only one-fourth of those infected display tertiary symptoms. These can be benign or incapacitating and even fatal; almost any part of the body may be attacked. Syphilis can spread to a fetus from an infected mother. Other species of Treponema cause similar but milder, nonsexually transmitted forms of syphilis (see yaws). Several blood tests can detect syphilis, even during latency. Antibiotic treatment is effective.
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Paul Ehrlich Summary
Paul Ehrlich was a German medical scientist known for his pioneering work in hematology, immunology, and chemotherapy and for his discovery of the first effective treatment for syphilis. He received the Nobel Prize for Physiology or Medicine in 1908 jointly with Élie Metchnikoff. Ehrlich was born
Paracelsus Summary
Paracelsus was a German-Swiss physician and alchemist who established the role of chemistry in medicine. He published Der grossen Wundartzney (Great Surgery Book) in 1536 and a clinical description of syphilis in 1530. Paracelsus, who was known as Theophrastus when he was a boy, was the only son of