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Several sites in the reproductive system either are vulnerable to chemicals or can be manipulated by drugs. Within the central nervous system, sensitive sites include the hypothalamus (and adjacent areas of the brain) and the anterior lobe of the pituitary gland. Regions outside the brain that are vulnerable include the gonads (i.e., the ovaries in the female and the testes in the male), the uterus in the female, and the prostate gland in the male. The body has anatomic or physiological barriers that tend to protect the reproductive system. The so-called placental barrier and the blood-testis barrier impede certain chemicals, ...(100 of 9029 words)